Dimethylamine → 5-(Dimethylamino)pentanenitrile

HRID 1264298ノート

反応式

HRID 1264298 の反応式
[CH3:1][NH:2][CH3:3].Br[CH2:5][CH2:6][CH2:7][CH2:8][C:9]#[N:10]>[OH-].[Na+]>[CH3:1][N:2]([CH3:3])[CH2:5][CH2:6][CH2:7][CH2:8][C:9]#[N:10]

参加物

4

反応物 2

HCID 674DimethylamineHCID 794355-Bromopentanenitrile

生成物 1

HCID 53056495-(Dimethylamino)pentanenitrile

試薬・触媒・溶媒 1

HCID 14798Sodium Hydroxide溶媒

実験手順

A mixture of dimethylamine (4 mL, 40% in water) and 5-bromo-pentanenitrile (2.3 mL, 20 mmol) is stirred for 24 h. The resulting reaction mixture is diluted with sodium hydroxide solution (10 mL, 5M) and extracted with ether. The ether extract is dried over K2CO3 and concentrated under reduced pressure to give an oil (1.5 g) which is used without further purification.

後処理

  1. customThe resulting reaction mixture
  2. extractionextracted with ether
  3. extractionThe ether extract
  4. dry with materialis dried over K2CO3
  5. concentrationconcentrated under reduced pressure

出典と根拠

ORDレコード
ord-44a70acd3b3c45d787ed0e4e7e0076b1
出典データセット
uspto-grants-2003_04
特許番号
US06541505B1

反応ノート

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