Water → 1-Ethenyl-2-(iodomethyl)benzene

HRID 1264541

反応式

HRID 1264541 の反応式
Cl[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]=[CH2:10].[I-:11].[Na+].O>CC(C)=O>[I:11][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]=[CH2:10]

参加物

5

反応物 3

HCID 962WaterHCID 5238Sodium IodideHCID 897571-(Chloromethyl)-2-ethenylbenzene

生成物 1

HCID 158305741-Ethenyl-2-(iodomethyl)benzene収率 95%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

Dissolve 1-chloromethyl-2-vinyl-benzene (4.0 g, 26 mmol) in acetone (100 mL) and add sodium iodide (4.5 g, 30 mmol). Heat at gentle reflux for 30 minutes. Cool, add water (150 mL) and extract with pentane (200 mL). Dry (MgSO4) and evaporate the solvent in vacuo to give 1-iodomethyl-2-vinyl-benzene (95%).

後処理

  1. temperatureHeat
  2. temperatureat gentle reflux for 30 minutes
  3. temperatureCool
  4. extractionextract with pentane (200 mL)
  5. dry with materialDry (MgSO4)
  6. customevaporate the solvent in vacuo

出典と根拠

ORDレコード
ord-62360d8ce7814f55b21d359d07ada96b
出典データセット
uspto-grants-2003_04
特許番号
US06544980B2

関連ノート

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