Hydrogen Bromide → 2-(Bromomethyl)-4-methyl-1-nitrobenzene
反応式
[BrH:1].[CH3:2][C:3]1[CH:4]=[CH:5][C:6]([N+:11]([O-:13])=[O:12])=[C:7]([CH:10]=1)[CH2:8]O>C(O)(=O)C>[CH3:2][C:3]1[CH:4]=[CH:5][C:6]([N+:11]([O-:13])=[O:12])=[C:7]([CH:10]=1)[CH2:8][Br:1]参加物
4
実験手順
To a cooled (ice-water bath) mixture of 30% HBr in acetic acid (3 ml) was added 2.5 g 5-methyl-2-nitrobenzyl alcohol and the chilled solution stirred for 2 hours. The mixture was poured into ice-water and extracted with diethyl ether. The extract was washed with H2O, brine and the solvent removed under vacuum to give a mixture of product (50%) and starting material (50%).
後処理
- temperatureTo a cooled
- extractionextracted with diethyl ether
- washThe extract was washed with H2O, brine
- customthe solvent removed under vacuum
- customto give
出典と根拠
- ORDレコード
- ord-5ee68db543654f1f8a74c0e4c242249e
- 出典データセット
- uspto-grants-2003_04
- 特許番号
- US06544984B1
反応ノート
読み込み中…