HCID 69688164、化合物 → (2-Amino-5-azetidin-1-yl-4-trifluoromethyl-phenyl)-carbamic acid tert.-butyl ester
反応式
[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[C:12]([N:14]2[CH2:17][CH2:16][CH2:15]2)[C:11]([C:18]([F:21])([F:20])[F:19])=[CH:10][C:9]=1[N+:22]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pt]>[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[C:12]([N:14]2[CH2:17][CH2:16][CH2:15]2)[C:11]([C:18]([F:20])([F:21])[F:19])=[CH:10][C:9]=1[NH2:22])([CH3:4])([CH3:2])[CH3:3]参加物
3
実験手順
The title compound was prepared from (5-azetidin-1-yl-2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert.-butyl ester (Example C15) by hydrogenation with 5% Pt/C according to the general procedure J (method a).
出典と根拠
- ORDレコード
- ord-768a41e64e304823a51595db700ce21f
- 出典データセット
- uspto-grants-2003_04
- 特許番号
- US06544985B2
反応ノート
読み込み中…