Methanol → 5-Methoxy-2-nitro-4-pyrrol-1-yl-phenylamine

HRID 1266730

反応式

HRID 1266730 の反応式
Cl[C:2]1[C:3]([N:12]2[CH:16]=[CH:15][CH:14]=[CH:13]2)=[CH:4][C:5]([N+:9]([O-:11])=[O:10])=[C:6]([NH2:8])[CH:7]=1.[CH3:17][OH:18].[OH-].[K+]>CS(C)=O>[CH3:17][O:18][C:2]1[C:3]([N:12]2[CH:16]=[CH:15][CH:14]=[CH:13]2)=[CH:4][C:5]([N+:9]([O-:11])=[O:10])=[C:6]([NH2:8])[CH:7]=1

参加物

5

反応物 3

HCID 887MethanolHCID 14797Potassium HydroxideHCID 185488595-Chloro-2-nitro-4-pyrrol-1-yl-phenylamine

生成物 1

HCID 185487175-Methoxy-2-nitro-4-pyrrol-1-yl-phenylamine

試薬・触媒・溶媒 1

HCID 679Dimethyl Sulfoxide溶媒

実験手順

The title compound was prepared from 5-chloro-2-nitro-4-pyrrol-1-yl-phenylamine (Example F3) (5.94 g, 25 mmol), methanol (25 mL) and KOH (1.98 g, 30 mmol) in DMSO (25 mL) according to the general procedure E. Obtained as an orange solid (5.88 g).

出典と根拠

ORDレコード
ord-e6ee15db5ebc44d9980b62679a2b0bb5
出典データセット
uspto-grants-2003_04
特許番号
US06548495B2

関連ノート

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