Trifluoroacetic acid → HCID 18548842、化合物
反応式
C(OC(=O)[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH3:15])[C:11]([N:16]2[CH:20]=[CH:19][CH:18]=[C:17]2[C:21]([CH3:24])([CH3:23])[CH3:22])=[CH:10][C:9]=1[NH:25][C:26](=[O:38])[CH2:27][C:28]([C:30]1[CH:35]=[CH:34][CH:33]=[C:32]([C:36]#[N:37])[CH:31]=1)=O)(C)(C)C.C(O)(C(F)(F)F)=O>C(Cl)Cl>[C:21]([C:17]1[N:16]([C:11]2[C:12]([O:14][CH3:15])=[CH:13][C:8]3[N:7]=[C:28]([C:30]4[CH:31]=[C:32]([CH:33]=[CH:34][CH:35]=4)[C:36]#[N:37])[CH2:27][C:26](=[O:38])[NH:25][C:9]=3[CH:10]=2)[CH:20]=[CH:19][CH:18]=1)([CH3:23])([CH3:24])[CH3:22]参加物
4
実験手順
The title compound was prepared from {4-(2-tert.-butyl-pyrrol-1-yl)-2-[3-(3-cyano-phenyl)-3-oxo-propionylamino]-5-methoxy-phenyl}-carbamic acid tert.-butyl ester (Example M19) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a yellow solid (22 mg).
出典と根拠
- ORDレコード
- ord-6576ff5ced31489da77f293e79ab9fb5