Hydrazine hydrate (1:1) → HCID 18544800、化合物

HRID 1266928ノート

反応式

HRID 1266928 の反応式
F[C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[C:6]([O:12][CH3:13])[N:5]=[C:4]([CH3:14])[N:3]=1.O.[NH2:16][NH2:17]>C(O)C>[NH:16]([C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[C:6]([O:12][CH3:13])[N:5]=[C:4]([CH3:14])[N:3]=1)[NH2:17]

参加物

4

反応物 2

HCID 24654Hydrazine hydrate (1:1)HCID 133793024-Fluoro-6-methoxy-2-methyl-5-(trifluoromethyl)pyrimidine

生成物 1

HCID 18544800HCID 18544800、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Next, a reaction flask was loaded with 4-fluoro-6-methoxy-2-methyl-5-(trifluoromethyl)-pyrimidine (22 g) and ethanol (40 ml), followed by dropwise addition of hydrazine monohydrate (10.5 g) to the flask in one hour with stirring. Then, after stirring for one hour, the reaction mixture was filtrated to give 4-hydrazino-6-methoxy-2-methyl-5-(trifluoromethyl)pyrimidine. By GC/MS analysis, a molecular ion peak of 222 was confirmed for this compound.

後処理

  1. stirringThen, after stirring for one hour
  2. filtrationthe reaction mixture was filtrated

出典と根拠

ORDレコード
ord-ef40c0aa281a4cbc8861ef1eea4bd4f1
出典データセット
uspto-grants-2003_04
特許番号
US06551682B1

反応ノート

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