Water → 4,4,5,5,6,6,7,7,7-Nonafluoroheptyl iodide

HRID 1267468ノート

反応式

HRID 1267468 の反応式
CS(O[CH2:6][CH2:7][CH2:8][C:9]([F:21])([F:20])[C:10]([F:19])([F:18])[C:11]([F:17])([F:16])[C:12]([F:15])([F:14])[F:13])(=O)=O.[I-:22].[Na+].O>CC(C)=O>[I:22][CH2:6][CH2:7][CH2:8][C:9]([F:21])([F:20])[C:10]([F:19])([F:18])[C:11]([F:17])([F:16])[C:12]([F:15])([F:14])[F:13]

参加物

5

反応物 3

HCID 962WaterHCID 5238Sodium IodideHCID 120167731-Methanesulfonyloxy-4,4,5,5,6,6,7,7,7-nonafluoroheptane

生成物 1

HCID 120167744,4,5,5,6,6,7,7,7-Nonafluoroheptyl iodide収率 87%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

1-Methanesulfonyloxy-4,4,5,5,6,6,7,7,7-nonafluoro-heptane (6.7 g, 18.8 mmol) and sodium iodide (8.5 g, 56.4 mmol) were stirred in acetone (400 ml) for 12 hours under heating. After the reaction was completed, water was added to the reaction mixture, which was then extracted with ether. The organic layer was washed with water and saturated aqueous sodium chloride, and then dried over anhydrous magnesium sulfate. The solvent was distilled off to give 1-iodo-4,4,5,5,6,6,7,7,7-nonafluoroheptane (6.33 g, Yield 87%) as a colorless oil.

後処理

  1. temperatureunder heating
  2. extractionwas then extracted with ether
  3. washThe organic layer was washed with water and saturated aqueous sodium chloride
  4. dry with materialdried over anhydrous magnesium sulfate
  5. distillationThe solvent was distilled off

出典と根拠

ORDレコード
ord-fad63775b7ea4eff888fb5a2e2a253e6
出典データセット
uspto-grants-2003_04
特許番号
US06552069B1

反応ノート

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