Benzyl Bromide → HCID 69471538、化合物

HRID 1271006ノート

反応式

HRID 1271006 の反応式
[F:1][CH2:2][C:3]([NH2:5])=[S:4].[CH2:6]([Br:13])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>C(Cl)(Cl)Cl.CCOCC>[BrH:13].[CH2:6]([S:4][C:3](=[NH:5])[CH2:2][F:1])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

参加物

5

反応物 2

HCID 7498Benzyl BromideHCID 167372062-Fluorothioacetamide

生成物 1

HCID 69471538HCID 69471538、化合物収率 54%

試薬・触媒・溶媒 2

HCID 3283Diethyl Ether溶媒HCID 6212Chloroform溶媒

実験手順

Fluorothioacetamide (3.39 g) and benzyl bromide (6.23 g) were refluxed in chloroform (40 ml), under nitrogen, for 16 h. After colling, the mixture was diluted with ether (200 ml) and the resulting orange solid filtered off. The solid was washed with more ether and dried over P2O5 in vacuo to give 5.19 g of the desired product.

後処理

  1. filtrationthe resulting orange solid filtered off
  2. washThe solid was washed with more ether
  3. dry with materialdried over P2O5 in vacuo

出典と根拠

ORDレコード
ord-129a09d650754e23b0d382883123fa6c
出典データセット
uspto-grants-2007_04
特許番号
USRE039576E1

反応ノート

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