3-(2,6dichloro-4-(benzyloxy)phenoxy)-1-propyl alcohol → HCID 18454988、化合物
反応式
[Cl:1][C:2]1[CH:12]=[C:11]([O:13]CC2C=CC=CC=2)[CH:10]=[C:9]([Cl:21])[C:3]=1[O:4][CH2:5][CH2:6][CH2:7][OH:8].[H][H]>[Pd].C(O)C>[Cl:1][C:2]1[CH:12]=[C:11]([OH:13])[CH:10]=[C:9]([Cl:21])[C:3]=1[O:4][CH2:5][CH2:6][CH2:7][OH:8]参加物
5
実験手順
This compound was prepared in a manner analogous to that of Step B of Example 1, by the treatment of 11.8 grams (0.036 mole) of 3-[2,6-dichloro-4-(phenylmethoxy)phenoxy]propan-1-ol with hydrogen gas in the presence of a catalytic amount of 10% palladium on carbon in ethanol using a Parr hydrogenation apparatus. Following the theoretical uptake of hydrogen, the reaction mixture was and filtered and concentrated under reduced pressure to a residue, yielding 8.0 grams of the subject compound.
後処理
- customThis compound was prepared in a manner analogous to that of Step B of Example 1
- filtrationfiltered
- concentrationconcentrated under reduced pressure to a residue
出典と根拠
- ORDレコード
- ord-3657d23dd5754bba8161abf3a73df7d6
- 出典データセット
- uspto-grants-2007_04
- 特許番号
- US07208450B2
反応ノート
読み込み中…