Thionyl Chloride → HCID 20544693、化合物

HRID 127444ノート

反応式

HRID 127444 の反応式
S(Cl)([Cl:3])=O.[Cl:5][C:6]1[CH:15]=[CH:14][C:9]2[O:10][CH2:11][CH2:12][O:13][C:8]=2[C:7]=1[C:16]([OH:18])=O>>[Cl:5][C:6]1[CH:15]=[CH:14][C:9]2[O:10][CH2:11][CH2:12][O:13][C:8]=2[C:7]=1[C:16]([Cl:3])=[O:18]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 20544734HCID 20544734、化合物

生成物 1

HCID 20544693HCID 20544693、化合物収率 93%

実験手順

56 ml of thionyl chloride, 28 g of 6-chloro-1,4-benzodioxane-5-carboxylic acid were introduced into a 250 ml balloon flask provided with a stirrer, a condenser and a thermometer. The mixture was heated at the reflux temperature for 30 minutes. The excess of thionyl chloride was removed by distillation under reduced pressure. 28.5 g of 6-chloro-1,4-benzodioxane-5-carbonyl chloride were obtained (M.P.: 50° C.; yield: 93%).

後処理

  1. customprovided with a stirrer, a condenser
  2. temperatureThe mixture was heated at the reflux temperature for 30 minutes
  3. customThe excess of thionyl chloride was removed by distillation under reduced pressure

出典と根拠

ORDレコード
ord-c9d51060217d442490e3f84af25b0bc1
出典データセット
uspto-grants-1981_03
特許番号
US04255580

反応ノート

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