4-(4-Fluorophenoxy)-2-(prop-2-en-1-yl)phenol → 4-(4-Fluorophenoxy)-2-propylphenol
反応式
[F:1][C:2]1[CH:18]=[CH:17][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[C:9]([CH2:14][CH:15]=[CH2:16])[CH:8]=2)=[CH:4][CH:3]=1>C(OCC)(=O)C.[Pd]>[F:1][C:2]1[CH:18]=[CH:17][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[C:9]([CH2:14][CH2:15][CH3:16])[CH:8]=2)=[CH:4][CH:3]=1参加物
4
実験手順
A solution of 4-(4-fluorophenoxy)-2-allylphenol (2.30 g, 9.42 mmol) and 5% Pd/C (0.90 g) in ethyl acetate (30 mL) was stirred under H2 atmosphere for 3 h at room temperature. The reaction mixture was filtered through a short pad of silica gel and concentrated in vacuo to afford the title compound which was used as is.
後処理
- filtrationThe reaction mixture was filtered through a short pad of silica gel
- concentrationconcentrated in vacuo
出典と根拠
- ORDレコード
- ord-8fe5846a9bc24a6c8e28198bca7e48ed
- 出典データセット
- uspto-grants-2000_12
- 特許番号
- US06160000
反応ノート
読み込み中…