N-bromobutanimide → 2-Bromomethyl-8-methyl-5H-dibenzo[a,d]cyclohepten-5-one

HRID 1275902ノート

反応式

HRID 1275902 の反応式
[CH3:1][C:2]1[CH:18]=[CH:17][C:5]2[C:6](=[O:16])[C:7]3[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][C:8]=3[CH:9]=[CH:10][C:4]=2[CH:3]=1.[Br:19]N1C(=O)CCC1=O>C(OCC)(=O)C>[Br:19][CH2:1][C:2]1[CH:18]=[CH:17][C:5]2[C:6](=[O:16])[C:7]3[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][C:8]=3[CH:9]=[CH:10][C:4]=2[CH:3]=1

参加物

4

反応物 2

HCID 67184N-bromobutanimideHCID 221172592,8-dimethyl-5H-dibenzo[a,d][7]annulen-5-one

生成物 1

HCID 221172722-Bromomethyl-8-methyl-5H-dibenzo[a,d]cyclohepten-5-one

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

The product of step (i) (2.0 g) and N-bromosuccinimide (1.52 g) in ethyl acetate (80ml) was irradiated with a 500 W halogen lamp for 4 hours. The reaction mixture was washed with brine, dried (MgSO4) and evaporated under reduced pressure. Purification was by chromatography eluting with toluene. Used directly in the next step.

後処理

  1. washThe reaction mixture was washed with brine
  2. dry with materialdried (MgSO4)
  3. customevaporated under reduced pressure
  4. customPurification
  5. washeluting with toluene

出典と根拠

ORDレコード
ord-4d603e7f5bba488d825ad0603cbf16b3
出典データセット
uspto-grants-2000_12
特許番号
US06162808

反応ノート

読み込み中…