Thionyl Chloride → Methyl 2-chloro-3-chlorocarbonyl-4-methylsulfonylbenzoate
反応式
S(Cl)([Cl:3])=O.[Cl:5][C:6]1[C:15]([C:16](O)=[O:17])=[C:14]([S:19]([CH3:22])(=[O:21])=[O:20])[CH:13]=[CH:12][C:7]=1[C:8]([O:10][CH3:11])=[O:9]>CN(C)C=O.C1(C)C=CC=CC=1>[Cl:5][C:6]1[C:15]([C:16]([Cl:3])=[O:17])=[C:14]([S:19]([CH3:22])(=[O:21])=[O:20])[CH:13]=[CH:12][C:7]=1[C:8]([O:10][CH3:11])=[O:9]参加物
5
実験手順
2 drops of dimethylformamide and 11.9 g (0.1 mol) of thionyl chloride were added to a solution of 6.0 g (0.021 mol) of methyl 2-chloro-3-hydroxycarbonyl-4-methylsulfonylbenzoate and 50 ml of dry toluene. The solution was heated under reflux for 4 hours. Removal of the solvent under reduced pressure gave 6.2 g of methyl 2-chloro-3-chlorocarbonyl-4-methylsulfonylbenzoate.
後処理
- temperatureThe solution was heated
- temperatureunder reflux for 4 hours
- customRemoval of the solvent under reduced pressure
出典と根拠
- ORDレコード
- ord-3f24f49e6b784ebb932cfb7b42a4d25c
- 出典データセット
- uspto-grants-2000_12
- 特許番号
- US06165944
反応ノート
読み込み中…