Sodium Carbonate → 3-Isoxazolamine, 5-(1,1-dimethylethyl)-
反応式
[C:1]([CH2:7][C:8]#[N:9])(=[O:6])[C:2]([CH3:5])([CH3:4])[CH3:3].C(=O)([O-])[O-].[Na+].[Na+].S(O)(O)(=O)=O.[NH2:21]O>O>[NH2:9][C:8]1[CH:7]=[C:1]([C:2]([CH3:5])([CH3:4])[CH3:3])[O:6][N:21]=1参加物
5
実験手順
A suspension of pivaloylacetonitrile (12.52 g), sodium carbonate (8.74 g) and water (200 ml) is stirred and mixed with hydroxylamine sulfate (9.03 g) at 25° C. pH 7.11. The reaction mixture is treated as in Example 2 to give 3-amino-5-t-butylisoxazole (12.01 g). Yield, 85.7%. Purity, 95.8%.
後処理
- additionThe reaction mixture is treated as in Example 2
出典と根拠
- ORDレコード
- ord-fb681df70af54e46886ea03fbdfbd7f2
- 出典データセット
- uspto-grants-1981_03
- 特許番号
- US04256899
反応ノート
読み込み中…