Triethylamine → 3-Isoxazolamine, 5-(1,1-dimethylethyl)-
反応式
[C:1]([CH2:7][C:8]#[N:9])(=[O:6])[C:2]([CH3:5])([CH3:4])[CH3:3].C([N:12](CC)CC)C.S(O)(O)(=O)=O.NO>O>[NH2:9][C:8]1[CH:7]=[C:1]([C:2]([CH3:5])([CH3:4])[CH3:3])[O:6][N:12]=1参加物
5
実験手順
A suspension of pivaloylacetonitrile (12.52 g) and triethylamine (11.27 g) in water (200 ml) is stirred and mixed with hydroxylamine sulfate (9.03 g). pH 8.22. The reaction mixture is treated as in Example 2 to give 3-amino-5-t-butylisoxazole (11.45 g; yield, 81.7%).
後処理
- additionThe reaction mixture is treated as in Example 2
出典と根拠
- ORDレコード
- ord-d73c023895844ceaa0b5ec960b928bde
- 出典データセット
- uspto-grants-1981_03
- 特許番号
- US04256899
反応ノート
読み込み中…