Isopropylamine → HCID 12944288、化合物

反応式

[O:1]1[CH:3]([CH2:4][CH2:5][C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:2]1.[CH:18]([NH2:21])([CH3:20])[CH3:19]>>[CH:18]([NH:21][CH2:2][CH:3]([OH:1])[CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)([CH3:20])[CH3:19]

参加物

反応物 2

HCID 6363Isopropylamine

HCID 12944286HCID 12944286、化合物

生成物 1

HCID 12944288HCID 12944288、化合物

実験手順

Following a precedure similar to that of Example 32, 1,2-epoxy-4-(1,1'-biphenyl-2-yl)butane was reacted with isopropylamine to provide N-isopropyl-2-hydroxy-4-(1,1'-biphenyl-2-yl)butylamine. The amine base so formed was reacted with hydrogen chloride to provide N-isopropyl-2-hydroxy-4-(1,1'-biphenyl-2-yl)butylaminium chloride. M.P. 153°-154° C.

出典と根拠

ORDレコード: ord-15ff1d5c6bfe4cf5a785860e552ed7c8
出典データセット: uspto-grants-1981_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04277471

反応ノート

読み込み中…