Hydrochloric Acid → HCID 14067481、化合物
反応式
[CH3:1][O:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[N:6]2[CH:13]=[C:14]([C:16]([O:18]CC)=[O:17])[N:15]=[C:5]2[CH:4]=1.[OH-].[Na+].Cl>C(O)C.O>[CH3:1][O:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[N:6]2[CH:13]=[C:14]([C:16]([OH:18])=[O:17])[N:15]=[C:5]2[CH:4]=1参加物
6
実験手順
250 mg of ethyl 5-methoxyimidazo-[1,2-a]-quinoline-2-carboxylate in 20 ml of ethanol and 10 ml of water was hydrolyzed with 2 ml of N sodium hydroxide solution and was then acidified with 2.2 ml of N hydrochloric acid as in Example 36 to obtain 5-methoxyimidazo-[1,2-a]-quinoline-2-carboxylic acid as colorless needles melting at 244°-247° C. The I.R. spectrum indicated that the compound existed entirely in the zwitterionic form.
出典と根拠
- ORDレコード
- ord-9c91d3715cf0449ba0ca4b81e342203e
- 出典データセット
- uspto-grants-1981_07
- 特許番号
- US04279912
反応ノート
読み込み中…