Glycol monoethyl ether → HCID 21163083、化合物

HRID 1278236ノート

反応式

HRID 1278236 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:12]3[N:13]=[CH:14][C:15]([C:16]([O:18][CH2:19][CH3:20])=[O:17])=[C:11]3[N:10]=[CH:9][CH:8]=2)[CH:2]=1.[CH2:21]([O:23]CCO)[CH3:22].[H-].[Na+].[H-]>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:12]3[N:13]=[CH:14][C:15]([C:16]([O:18][CH2:19][CH2:20][O:23][CH2:21][CH3:22])=[O:17])=[C:11]3[N:10]=[CH:9][CH:8]=2)[CH:2]=1

参加物

5

反応物 4

HCID 8076Glycol monoethyl etherHCID 24758Sodium hydrideHCID 166653HydrideHCID 11196438ETHYL 7-(PYRIDIN-3-YL)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLATE

生成物 1

HCID 21163083HCID 21163083、化合物

実験手順

To a mixture of ethyl 7-(3-pyridyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate and 2-ethoxyethanol is added sodium hydride. After the hydride is reacted, the mixture is heated on a steam bath for 12 hours. The solvent is removed and the residue is acidified with dilute acetic acid to give the product of the example.

後処理

  1. temperaturethe mixture is heated on a steam bath for 12 hours
  2. customThe solvent is removed
  3. customto give the product of the example

出典と根拠

ORDレコード
ord-990130447918491cb3a08531fd5ef381
出典データセット
uspto-grants-1981_07
特許番号
US04281000

反応ノート

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