4-Hydroxybenzaldehyde → HCID 5153357、化合物
反応式
[Cl:1][C:2]1[CH:14]=[CH:13][C:5]([C:6]([NH:8][CH2:9][C:10]([OH:12])=[O:11])=O)=[CH:4][CH:3]=1.[OH:15][C:16]1[CH:23]=[CH:22][C:19]([CH:20]=O)=[CH:18][CH:17]=1.[C:24](OC(=O)C)(=[O:26])[CH3:25]>C(O)C>[C:24]([O:15][C:16]1[CH:23]=[CH:22][C:19]([CH:20]=[C:9]2[C:10](=[O:11])[O:12][C:6]([C:5]3[CH:4]=[CH:3][C:2]([Cl:1])=[CH:14][CH:13]=3)=[N:8]2)=[CH:18][CH:17]=1)(=[O:26])[CH3:25]参加物
5
実験手順
A mixture of 60 g of N-(p-chlorobenzoyl)glycine, 34.5 g of p-hydroxybenzaldehyde, 23 g of fused sodium acetate and 170 ml of acetic anhydride was heated under reflux for 1 hour. The reaction mixture was cooled slightly and 400 ml of ethanol was added. A solid precipitated on cooling and was filtered and washed with cold ethanol and cold water. An analytical sample was made by recrystallization from CCL4 /EtOH/AcOH, m.p. 185-186.