Sulfuric acid magnesium salt (1:1) → Methyl (2E)-{[(2,4-dimethoxyphenyl)methyl]imino}acetate

HRID 127884

反応式

HRID 127884 の反応式
[CH3:1][O:2][C:3]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[CH:7][C:4]=1[CH2:5][NH2:6].S([O-])([O-])(=O)=O.[Mg+2].[C:19]([O:23][CH3:24])(=[O:22])[CH:20]=O>C(Cl)Cl>[CH3:1][O:2][C:3]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[CH:7][C:4]=1[CH2:5][N:6]=[CH:20][C:19]([O:23][CH3:24])=[O:22]

参加物

5

反応物 3

HCID 24083Sulfuric acid magnesium salt (1:1)HCID 70205Acetic acid, 2-oxo-, methyl esterHCID 5972502,4-Dimethoxybenzylamine

生成物 1

HCID 23470137Methyl (2E)-{[(2,4-dimethoxyphenyl)methyl]imino}acetate

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

実験手順

To a mixture containing 16.82 g (0.101 mole) of 2,4-dimethoxybenzylamine and anhydrous magnesium sulfate in 150 ml of methylene chloride at 25° is added a solution of 10.05 g (0.114 mole) of methyl glyoxalate in 20 ml of methylene chloride. The reaction mixture is stirred at room temperature overnight (15 hours) and then is filtered and the solvents are removed in vacuo to afford the imine as a dark orange gum.

後処理

  1. filtrationis filtered
  2. customthe solvents are removed in vacuo

出典と根拠

ORDレコード
ord-3a6afd3455a641c0957d904292864f54
出典データセット
uspto-grants-1981_03
特許番号
US04257947

関連ノート

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