1-Bromooctadecane → N,N-Bis(2-Hydroxyethyl)-N'-Octadecyl-1,3-Propanediamine

HRID 127987

反応式

HRID 127987 の反応式
[CH2:1](Br)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[NH2:20][CH2:21][CH2:22][CH2:23][N:24]([CH2:28][CH2:29][OH:30])[CH2:25][CH2:26][OH:27]>C(O)C1C=CC=CC=1>[OH:30][CH2:29][CH2:28][N:24]([CH2:25][CH2:26][OH:27])[CH2:23][CH2:22][CH2:21][NH:20][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

参加物

4

反応物 2

HCID 82181-BromooctadecaneHCID 21088(3-Aminopropyl)diethanolamine

生成物 1

HCID 20433008N,N-Bis(2-Hydroxyethyl)-N'-Octadecyl-1,3-Propanediamine

試薬・触媒・溶媒 1

HCID 244Benzyl Alcohol溶媒

実験手順

A solution of octadecyl bromide (26.65 g., 80 mM.), N-(3-aminopropyl)diethanolamine (105 g., 640 mM.) and benzyl alcohol (120 ml.) is heated at 130° C. for twenty-three hours. The benzyl alcohol is removed in vacuo (0.1 mm. Hg, and 75° C.) and the residue taken up in methylene chloride (250 ml.). The methylene chloride solution is washed with aqueous sodium hydroxide (1 N) then with brine. It is dried (Na2SO4), concentrated, and distilled; b.p. 242°-246° C. at 0.1 mm Hg. The product is a waxy solid.

後処理

  1. customThe benzyl alcohol is removed in vacuo (0.1 mm. Hg, and 75° C.)
  2. washThe methylene chloride solution is washed with aqueous sodium hydroxide (1 N)
  3. dry with materialIt is dried (Na2SO4)
  4. concentrationconcentrated
  5. distillationdistilled

出典と根拠

ORDレコード
ord-081cf7686d4640d89305cd2c85ebec99
出典データセット
uspto-grants-1981_03
特許番号
US04258061

関連ノート

読み込み中…