Pyridine → 1,3,5-Triiodobenzene-2,4,6-trialdehyde
反応式
[I:1][C:2]1[C:7]([CH2:8][OH:9])=[C:6]([I:10])[C:5]([CH2:11][OH:12])=[C:4]([I:13])[C:3]=1[CH2:14][OH:15].C(N(CC)CC)C.N1C=CC=CC=1>CS(C)=O>[I:1][C:2]1[C:3]([CH:14]=[O:15])=[C:4]([I:13])[C:5]([CH:11]=[O:12])=[C:6]([I:10])[C:7]=1[CH:8]=[O:9]参加物
5
反応条件
- 温度
- 0 °C
実験手順
1,3,5-Triiodo-2,4,6-trihydroxymethylbenzene (4.5 g, 8.2 mmol) was dissolved in DMSO (80 ml). Triethylamine (51.7 ml, 371 mmol) and pyridine.SO3 (11.8 g, 74.2 mmol) were added and the mixture was stirred for two hours. The two phases were separated and the lower phase was cooled to 0° C., poured into water (150 ml) and stirred for 30 min at 0° C. The white solid was collected by filtration, washed with water and dried. Yield: 3.0 g (67%).
後処理
- additionSO3 (11.8 g, 74.2 mmol) were added
- customThe two phases were separated
- additionpoured into water (150 ml)
- stirringstirred for 30 min at 0° C
- filtrationThe white solid was collected by filtration
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-e82eb6646ed54fbca39e29f276e669c3
- 出典データセット
- uspto-grants-2002_09
- 特許番号
- US06448442B1
反応ノート
読み込み中…