Methyl iodide → 5,6-Dichloro2-(4-formylphenyl)-1-methylbenzimidazole

反応式

[Cl:1][C:2]1[C:18]([Cl:19])=[CH:17][C:5]2[N:6]=[C:7]([C:9]3[CH:14]=[CH:13][C:12]([CH:15]=[O:16])=[CH:11][CH:10]=3)[NH:8][C:4]=2[CH:3]=1.I[CH3:21]>>[Cl:19][C:18]1[C:2]([Cl:1])=[CH:3][C:4]2[N:8]([CH3:21])[C:7]([C:9]3[CH:10]=[CH:11][C:12]([CH:15]=[O:16])=[CH:13][CH:14]=3)=[N:6][C:5]=2[CH:17]=1

参加物

反応物 2

HCID 6328Methyl iodide

HCID 184267935,6-Dichloro-2-(4-formylphenyl)benzimidazole

生成物 1

HCID 184267875,6-Dichloro2-(4-formylphenyl)-1-methylbenzimidazole

実験手順

5,6-Dichloro2-(4-formylphenyl)-1-methylbenzimidazole was prepared from 5,6-dichloro-2-(4-formylphenyl)benzimidazole obtained in Example 13 and iodomethane by following General Procedure 3.

出典と根拠

ORDレコード: ord-a657b8c9260f4374a2b48a0b44410a68
出典データセット: uspto-grants-2002_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06452014B1

反応ノート

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