N-bromobutanimide → 2-Bromo-6-chlorobenzyl bromide

HRID 128244ノート

反応式

HRID 128244 の反応式
[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[CH3:9].[Br:10]N1C(=O)CCC1=O>C(Cl)(Cl)(Cl)Cl>[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[CH2:9][Br:10]

参加物

4

反応物 2

HCID 67184N-bromobutanimideHCID 1235522-Bromo-6-chlorotoluene

生成物 1

HCID 27568722-Bromo-6-chlorobenzyl bromide

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

2-bromo-6-chlorotoluene (20.55 g) and N-bromosuccinimide (19.6 g) were stirred together in carbon tetrachloride (100 ml) under reflux for 22 hours exposure to radiation from an infrared lamp. The resulting solution was cooled in ice, filtered and evaporated to yield the title product which was dissolved in petroleum ether (60-80). Part was recrystallised therefrom as pink needles (8.5 g) and part was recovered by evaporation as a dark orange solid (17.7 g) (total yield 26.2 g. 92%).

後処理

  1. temperatureunder reflux for 22 hours exposure to radiation from an infrared lamp
  2. temperatureThe resulting solution was cooled in ice
  3. filtrationfiltered
  4. customevaporated

出典と根拠

ORDレコード
ord-1beeabfd933d4bed91e4baad702c8eeb
出典データセット
uspto-grants-1981_03
特許番号
US04259349

反応ノート

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