N-bromobutanimide → HCID 21520278、化合物
反応式
[Br:1]N1C(=O)CCC1=O.[CH2:9]([C:11]1[C:19]2[O:18][C:17]([C:20]3([CH3:25])[O:24][CH2:23][CH2:22][O:21]3)=[CH:16][C:15]=2[CH:14]=[CH:13][CH:12]=1)[CH3:10]>C(Cl)(Cl)(Cl)Cl>[Br:1][CH:9]([C:11]1[C:19]2[O:18][C:17]([C:20]3([CH3:25])[O:24][CH2:23][CH2:22][O:21]3)=[CH:16][C:15]=2[CH:14]=[CH:13][CH:12]=1)[CH3:10]参加物
4
反応条件
- 温度
- 0 °C
実験手順
28.0 g of recrystallized N-bromosuccinimide were added to a solution of 32.5 g of 7-ethyl-2-(2-methyl-1,3-dioxolan-2-yl)benzofuran in 480 ml of carbon tetrachloride. The resulting suspension was stirred and heated under reflux for 12 hours. The mixture was cooled overnight at 0°C, precipitated succinimide was filtered off and the filtrate was evaporated at 30°C under reduced pressure. There was thus obtained crude 7-(1'-bromoethyl)-2-(2-methyl-1,3-dioxolan-2-yl) benzofuran which was used immediately in the next stage. The structure of this compound was confirmed by spectral data.