Methyl chloroformate → 1-methoxycarbonyl-S-methylisothiourea
反応式
S(O)(O)(=O)=O.[CH3:6][S:7][C:8](=[NH:10])[NH2:9].Cl[C:12]([O:14][CH3:15])=[O:13].[OH-].[K+]>O>[NH2:10][C:8](=[N:9][C:12](=[O:13])[O:14][CH3:15])[S:7][CH3:6]参加物
5
実験手順
To a solution of 69.5 parts of 2-methyl-2-thiopseudourea sulfate and 47 parts of methyl chloroformate in 1000 parts of water at 0°C is added dropwise 56.9 parts of potassium hydroxide in 200 parts of water. The reaction mixture is stirred at room temperature for 3 hours and then extracted with methylene chloride. The methylene chloride extract is dried and the solvent evaporated at reduced pressure to give 45 g of methyl N-(1-amino-1-methylthiomethylene)carbamate melting at 72°-77°C.
後処理
- extractionextracted with methylene chloride
- extractionThe methylene chloride extract
- customis dried
- customthe solvent evaporated at reduced pressure
出典と根拠
- ORDレコード
- ord-a30614a363c64df48d24387f4ca58efc
- 出典データセット
- uspto-grants-1976_08
- 特許番号
- US03973947
反応ノート
読み込み中…