Salicylic Acid → 2-(Dichloromethyl)phenol
反応式
[C:1](O)(=O)[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].S(Cl)(Cl)=O.[Cl-:15].[Al+3].[Cl-:17].[Cl-]>>[CH:1]([Cl:17])([Cl:15])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4]参加物
4
反応条件
- 温度
- 42.5 °C
実験手順
A mixture of 10 grams salicylic acid, 7 ml of thionyl chloride, and 0.02 gram of aluminum chloride was heated at 40 to 45°C. for 11/2 hours. The excess thionyl chloride was removed in vacuum and the salicylyl chloride reaction product can be used without further purification.
後処理
- customThe excess thionyl chloride was removed in vacuum
- customthe salicylyl chloride reaction product
- customcan be used without further purification
出典と根拠
- ORDレコード
- ord-3e83c12fe1db40ba8056d1044542bbe6
- 出典データセット
- uspto-grants-1976_08
- 特許番号
- US03975532
反応ノート
読み込み中…