Hydrazine hydrate (1:1) → 2,3,5-Trichloro-6-hydrazinylpyrazine

HRID 1283729ノート

反応式

HRID 1283729 の反応式
[Cl:1][C:2]1[N:7]=[C:6]([Cl:8])[C:5]([Cl:9])=[N:4][C:3]=1Cl.O.[NH2:12][NH2:13]>O1CCOCC1.C(O)C>[Cl:1][C:2]1[C:3]([NH:12][NH2:13])=[N:4][C:5]([Cl:9])=[C:6]([Cl:8])[N:7]=1

参加物

5

反応物 2

HCID 24654Hydrazine hydrate (1:1)HCID 311820Tetrachloropyrazine

生成物 1

HCID 215166242,3,5-Trichloro-6-hydrazinylpyrazine

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 312751,4-Dioxane溶媒

反応条件

温度
23 °C

実験手順

A solution was prepared by dissolving 21.8 grams of tetrachloropyrazine in 100 milliliters of dioxane. The solution was diluted with 250 milliliters of ethanol and 15 milliliters of hydrazine hydrate was slowly added thereto. The temperature rose from 23°C to 37°C. The solution was held, with stirring, at 23°C for 20 minutes and the 3,5,6-trichloro-2-hydrazinopyrazine product was isolated by pouring the reaction mixture in water and filtering off the solid product. The product melted at 167°-168°C and was recovered in a yield of 20.2 grams (94 percent of theoretical).

後処理

  1. customA solution was prepared
  2. additionwas slowly added
  3. customrose from 23°C to 37°C

出典と根拠

ORDレコード
ord-3b4444603e294af58d9ae11a28c2bb20
出典データセット
uspto-grants-1976_08
特許番号
US03976644

反応ノート

読み込み中…