Dimethyl phenylphosphonite → methyl P-phenyl-2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenylphosphinate

HRID 1284424

反応式

HRID 1284424 の反応式
[Cl:1][C:2]1[CH:20]=[C:19]([C:21]([F:24])([F:23])[F:22])[CH:18]=[CH:17][C:3]=1[O:4][C:5]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[C:7]([N+]([O-])=O)[CH:6]=1.[C:25]1([P:31]([O:34]C)[O:32][CH3:33])[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>C(#N)C>[C:25]1([P:31]([C:7]2[CH:6]=[C:5]([O:4][C:3]3[CH:17]=[CH:18][C:19]([C:21]([F:24])([F:23])[F:22])=[CH:20][C:2]=3[Cl:1])[CH:10]=[CH:9][C:8]=2[N+:11]([O-:13])=[O:12])(=[O:34])[O:32][CH3:33])[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

参加物

4

反応物 2

HCID 76277Dimethyl phenylphosphoniteHCID 156238Benzene, 2-chloro-1-(3,4-dinitrophenoxy)-4-(trifluoromethyl)-

生成物 1

HCID 54521036methyl P-phenyl-2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenylphosphinate

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

Following the procedure of Example 1, a mixture of 4-(2-chloro-4-trifluoromethylphenoxy)-1,2-dinitrobenzene (2.0 g, 5.52 mmol) and dimethyl phenylphosphonite (1.4 g, 8.28 mmol) in 4 ml of acetonitrile is heated under reflux overnight. The crude product is purified to yield methyl P-phenyl-2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenylphosphinate, m/s 471 (M+).

後処理

  1. temperatureis heated
  2. temperatureunder reflux overnight
  3. customThe crude product is purified

出典と根拠

ORDレコード
ord-041d5245c1724cad8a4e591d6ebf83dc
出典データセット
uspto-grants-1986_01
特許番号
US04563310

関連ノート

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