Acetic Anhydride → HCID 20248673、化合物

HRID 1285269ノート

反応式

HRID 1285269 の反応式
S([O-])([O-])=O.[Na+].[Na+].S(O)(O)(=O)=O.[S:12]([NH:16][CH2:17][CH2:18][NH:19][C:20]1[CH:25]=[CH:24][C:23]([NH2:26])=[CH:22][CH:21]=1)([CH3:15])(=[O:14])=[O:13].[C:27](OC(=O)C)(=[O:29])[CH3:28]>O>[C:27]([NH:26][C:23]1[CH:24]=[CH:25][C:20]([NH:19][CH2:18][CH2:17][NH:16][S:12]([CH3:15])(=[O:13])=[O:14])=[CH:21][CH:22]=1)(=[O:29])[CH3:28]

参加物

5

反応物 3

HCID 7918Acetic AnhydrideHCID 24437Sodium SulfiteHCID 458930N-[2-(4-aminoanilino)ethyl]methanesulfonamide; sulfuric acid

生成物 1

HCID 20248673HCID 20248673、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

0.2 mol (25.2 g) of sodium sulphite is added, at ambient temperature, to a solution of 0.1 mol (32.7 g) of N-mesylaminoethyl-para-phenylenediamine sulphate in 150 ml of water, and 0.13 mol (13.17 g) of acetic anhydride is added gradually, whilst stirring. When the addition is complete, stirring is continued for one hour and the expected acetylated derivative, which has precipitated in crystalline form, is then filtered off. The product is drained, washed with water and dried in vacuo. After recrystallisation from alcohol and drying in vacuo, it melts at 130° C.

後処理

  1. additionis added gradually
  2. additionWhen the addition
  3. stirringstirring
  4. customthe expected acetylated derivative, which has precipitated in crystalline form
  5. filtrationis then filtered off
  6. washwashed with water
  7. customdried in vacuo
  8. customAfter recrystallisation from alcohol
  9. customdrying in vacuo, it melts at 130° C.

出典と根拠

ORDレコード
ord-c190d825d2b1470cb8ec930fde94b961
出典データセット
uspto-grants-1986_01
特許番号
US04566875

反応ノート

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