Methyl iodide → HCID 20248961、化合物

HRID 1285334ノート

反応式

HRID 1285334 の反応式
[CH2:1]([N:8]1[CH2:14][C:12](=[O:13])[NH:11][C:9]1=[S:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[I:15][CH3:16]>CO>[IH:15].[CH2:1]([N:8]1[CH2:14][C:12](=[O:13])[N:11]=[C:9]1[S:10][CH3:16])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 53685104-Imidazolidinone, 1-(phenylmethyl)-2-thioxo-

生成物 1

HCID 20248961HCID 20248961、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

1-Benzyl-2-thiohydantoin (8.07 g), iodomethane (10 ml) and methanol (50 ml) were warmed at 40°-42° C. for 8 hours. The reaction mixture was evaporated under reduced pressure, the residue was washed with diethyl ether and recrystallised from methanol-ethanol to give 1-benzyl-2-methylthio-2-imidazolin-4-one hydroiodide (4.86 g) m.p. 185°-190° C., as an impure light-buff coloured solid which was taken on to the next stage.

後処理

  1. customThe reaction mixture was evaporated under reduced pressure
  2. washthe residue was washed with diethyl ether
  3. customrecrystallised from methanol-ethanol

出典と根拠

ORDレコード
ord-323d82de3baf487685aa77e1d8b8ca82
出典データセット
uspto-grants-1986_01
特許番号
US04567176

反応ノート

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