Sodium Hydroxide → Thiourea, (2,3-dihydro-1H-inden-2-yl)-

HRID 1287896ノート

反応式

HRID 1287896 の反応式
C([NH:9][C:10]([NH:12][CH:13]1[CH2:21][C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:14]1)=[S:11])(=O)C1C=CC=CC=1.[OH-].[Na+]>O>[CH2:14]1[C:15]2[C:20](=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:21][CH:13]1[NH:12][C:10]([NH2:9])=[S:11]

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 21507070N-[(2,3-Dihydro-1H-inden-2-yl)carbamothioyl]benzamide

生成物 1

HCID 5277341Thiourea, (2,3-dihydro-1H-inden-2-yl)-

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

1-Benzoyl-3-(2-indanyl)thiourea (0.931 g.) and sodium hydroxide (0.500 g.) were refluxed in water (6 ml.) for 10 minutes. The mixture was cooled, extracted into chloroform and the chloroform extracts washed with water, dried (MgSO4) and evaporated to give a white solid. Recrystallisation from ethanol/water afforded the title compound as platelets (0.647 g.), m.p. 155.0° C.

後処理

  1. temperatureThe mixture was cooled
  2. extractionextracted into chloroform
  3. washthe chloroform extracts washed with water
  4. dry with materialdried (MgSO4)
  5. customevaporated
  6. customto give a white solid
  7. customRecrystallisation from ethanol/water

出典と根拠

ORDレコード
ord-9d356a509a3d42e49cfaea50e67a49e6
出典データセット
uspto-grants-1976_10
特許番号
US03985898

反応ノート

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