Ethanol → Ethyl 3-(5-methoxynaphthalen-2-yl)prop-2-enoate

HRID 1288210ノート

反応式

HRID 1288210 の反応式
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH:5]=[CH:6][C:7]([CH:13]=[CH:14][C:15]([OH:17])=[O:16])=[CH:8]2.S(=O)(=O)(O)O.[CH2:23](O)[CH3:24]>C(Cl)(Cl)Cl>[CH3:1][O:2][C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[CH:5]=[CH:6][C:7]([CH:13]=[CH:14][C:15]([O:17][CH2:23][CH3:24])=[O:16])=[CH:8]2

参加物

5

反応物 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 544606323-(5-Methoxynaphthalen-2-yl)prop-2-enoic acid

生成物 1

HCID 53889879Ethyl 3-(5-methoxynaphthalen-2-yl)prop-2-enoate

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

β-(5-methoxynaphth-2-yl)propenoic acid (0.075 moles) is allowed to reflux with 8-10 pieces of Orierite in absolute ethanol (20 ml) containing concentrated sulfuric acid (5 ml) for 21 hours. The cooled reaction mixture is diluted with chloroform and filtered hot. The filtrate is washed 3 times with water, once with 10% sodium bicarbonate and twice more with water. After drying over sodium sulfate, the solvent is removed to give ethyl β-(5-methoxynaphth-2-yl)propenoate.

後処理

  1. customThe cooled reaction mixture
  2. filtrationfiltered hot
  3. washThe filtrate is washed 3 times with water
  4. dry with materialAfter drying over sodium sulfate
  5. customthe solvent is removed

出典と根拠

ORDレコード
ord-8496e4432d85419ca57085f72da427d3
出典データセット
uspto-grants-1976_10
特許番号
US03987116

反応ノート

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