Formaldehyde → N-(1-benzotriazolylmethyl)-2,5-dimethylaniline

HRID 128822

反応式

HRID 128822 の反応式
[CH3:1][C:2]1[CH:8]=[CH:7][C:6]([CH3:9])=[CH:5][C:3]=1[NH2:4].[NH:10]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[N:12]=[N:11]1.[CH2:19]=O>CCO>[NH:10]1[C:14]2[CH:15]=[CH:16][CH:17]=[C:18]([CH2:19][NH:4][C:3]3[CH:5]=[C:6]([CH3:9])[CH:7]=[CH:8][C:2]=3[CH3:1])[C:13]=2[N:12]=[N:11]1

参加物

5

反応物 3

HCID 712FormaldehydeHCID 72592,5-DimethylanilineHCID 178418385HCID 178418385、化合物

生成物 1

HCID 178425127N-(1-benzotriazolylmethyl)-2,5-dimethylaniline収率 67.2%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of 2,5-dimethylaniline (27.4 g, 0.2 mol) and benzotriazole (23.8 g, 0.2 mol) in EtOH (300 mL) was stirred at 20° C. as 37% aqueous formaldehyde (16.1 g, 0.2 mol) was added gradually. After 30 minutes, the white solid which precipitated was collected and washed with EtOH to give N-(1-benzotriazolylmethyl)-2,5-dimethylaniline (33.9 g, 67% yield); mp (EtOH) 147°-149° C.

後処理

  1. additionwas added gradually
  2. customthe white solid which precipitated
  3. customwas collected
  4. washwashed with EtOH

出典と根拠

ORDレコード
ord-0e9609820ea5480ebed82b5d989ad9fd
出典データセット
uspto-grants-1995_11
特許番号
US05464861

関連ノート

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