Ethanol → HCID 85437759、化合物

HRID 1288232ノート

反応式

HRID 1288232 の反応式
[CH3:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)[O:5][CH2:6][C:7](=O)[CH3:8].C(O)C.Cl.[NH2:17][OH:18]>O>[CH3:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)[O:5][CH2:6][C:7](=[N:17][OH:18])[CH3:8]

参加物

5

反応物 3

HCID 702EthanolHCID 3095751-(3-Methylphenoxy)-2-propanoneHCID 443297Hydroxyamine hydrochloride

生成物 1

HCID 85437759HCID 85437759、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

1-(3-Methylphenoxy)propan-2-one (24.9 g.) and ethanol (100 ml.) were added to a solution of hydroxylamine hydrochloride (25 g.) and fused sodium acetate (25 g.) in water (110 ml.). The resulting solution was refluxed for 31/2 hours and evaporated to near dryness under reduced pressure. The residue was partitioned between water and ether. The ether extract was washed with water, dried over anhydrous potassium carbonate and evaporated. The residue was distilled to give a fraction, b.p. 159°-163°/12 mm. Redistillation gave 1-(3-methylphenoxy)propan-2-one oxime, b.p. 165°-167°/13 mm.

後処理

  1. temperatureThe resulting solution was refluxed for 31/2 hours
  2. customevaporated
  3. customThe residue was partitioned between water and ether
  4. extractionThe ether extract
  5. washwas washed with water
  6. dry with materialdried over anhydrous potassium carbonate
  7. customevaporated
  8. distillationThe residue was distilled
  9. customto give a fraction, b.p. 159°-163°/12 mm
  10. distillationRedistillation

出典と根拠

ORDレコード
ord-d963b52bf86449b7b7505952619039e9
出典データセット
uspto-grants-1976_10
特許番号
US03987158

反応ノート

読み込み中…