a Farnesol → Farnesyl isobutyrate

反応式

[OH:1][CH2:2][CH:3]=[C:4]([CH2:6][CH2:7][CH:8]=[C:9]([CH2:11][CH2:12][CH:13]=[C:14]([CH3:16])[CH3:15])[CH3:10])[CH3:5].[C:17](Cl)(=[O:21])[CH:18]([CH3:20])[CH3:19]>>[C:17]([O:1][CH2:2][CH:3]=[C:4]([CH2:6][CH2:7][CH:8]=[C:9]([CH2:11][CH2:12][CH:13]=[C:14]([CH3:16])[CH3:15])[CH3:10])[CH3:5])(=[O:21])[CH:18]([CH3:20])[CH3:19]

参加物

反応物 2

HCID 3327a Farnesol

HCID 62325Isobutyryl chloride

生成物 1

HCID 53690780Farnesyl isobutyrate収率 7.8%

実験手順

A mixture of farnesol (356 mg, 1.6 mmol) and isobutyryl chloride (407 mg, 3.8 mmol) was refluxed for 2 hours. Extraction with hexane, and purification yielded 35.9 mg (yield: 7.8%) of oil having the following physical properties.

後処理

temperaturewas refluxed for 2 hours
extractionExtraction
customwith hexane, and purification

出典と根拠

ORDレコード: ord-62198d5ca2b64db4ba0d8e928998ba71
出典データセット: uspto-grants-1995_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05466718

反応ノート

読み込み中…