ファルネソール (異性体混合物)

解説3,7,11-trimethyl-2,6,10-dodecatriene-1-ol．C15H26O(222.37)． シトロネラ油，レモングラス油，シクラメン油，ばら油などの香気成分．多くの精油には，このtrans-trans形異性体のみが存在する．無色透明な液体．沸点111 ℃(47 Pa)．d154"0.895．n25D"1.487．λmax 224 nm(ε 17.300)．非環式セスキテルペンアルコールの一例で，種々の植物精油中に含まれる。水に不溶，アルコール，エーテルに可溶の液体で，トランス-トランス異性体の沸点は 0.2mmHgの圧力下で 120℃である。香料原料として用いられる。また，ピロリン酸エステルはカロテノイド，ステロイドの生合成経路における中間体と考えられている。森北出版「化学辞典（第2版）

用途有機合成用試薬。香料原料

説明Farnesol has a characteristic flowery odor.

天然物の起源The presence of this terpene alcohol in nature has been reported in more than 30 essential oils; the levels are generally low (0.5 to 1.0%) with the exception of cabreuva, which contains up to 2 5% farensol, and the distillate from fowers of Oxystigma buccholtzii Harms which contains up to 18% farnesol Among the essential oils containing farnesol are lemongrass, Ceylon citronella, cananga, ambrette seeds, ylang-ylang, Acacia farnesiana, Peru balsam, palmarosa, tuberose, and others Reported found in apricot, citrus peel oils, grapefruit juice, strawberry jam, ginger, clove bud, hop oil, cardamom, ginger, thyme, beer, whiskey, basil, papaya, anise seed, German chamomile and Cympogon citratus oils

使用farnesol is described as a substance of high biological potential, capable of acting in the skin as a true bioactivator. A biological precursor and fatty alcohol, farnesol is one component of vitamin K. It is said to help smooth wrinkles, normalize sebum secretion, and increase the skin’s elasticity, tissue tension, and moisture-binding capability. It is able to penetrate the epidermis. In humans, farnesol is found in the skin and is involved in sterol biosynthesis. It is also used for its deodorant, odor-masking, and skin-soothing properties. In clinical studies, farnesol has demonstrated anti-microbial activity, though it is unclear if this remains the case once incorporated into a cosmetic formulation. It is widely present in vegetables and found in many essential oils (for example, acacia, lilac, lily of the valley, rose, orange blossom, oak moss, and sandalwood).