Sodium Iodide → HCID 86750329、化合物
反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][O:11][C:12]([C:14]2[N:15]3[CH:18]([CH:19]([CH3:33])[C:20]=2[S:21][CH:22]2[CH2:26][CH:25]([CH2:27]OS(C)(=O)=O)[O:24][CH2:23]2)[CH:17]([CH:34]([OH:36])[CH3:35])[C:16]3=[O:37])=[O:13])=[CH:6][CH:5]=1)([O-:3])=[O:2].[I-:38].[Na+]>CC(C)=O>[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][O:11][C:12]([C:14]2[N:15]3[CH:18]([CH:19]([CH3:33])[C:20]=2[S:21][CH:22]2[CH2:26][CH:25]([CH2:27][I:38])[O:24][CH2:23]2)[CH:17]([CH:34]([OH:36])[CH3:35])[C:16]3=[O:37])=[O:13])=[CH:6][CH:5]=1)([O-:3])=[O:2]参加物
4
実験手順
A mixture of 0.80 g of product from Example 57, 0.431 g of sodium iodide and 20 ml of acetone is heated at reflux temperature for 5 days. The reaction is concentrated in vacuo and the residue purified by chromatography (silica Gel: 80% ethyl acetate/hexane) to give 0.472 g of the desired product.
後処理
- temperature