Nitric Acid → 2,3-Dimethyl-5-nitroaniline

HRID 1290563ノート

反応式

HRID 1290563 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[CH3:9].[N+:10]([O-])([OH:12])=[O:11]>S(=O)(=O)(O)O>[CH3:9][C:3]1[C:4]([CH3:8])=[CH:5][C:6]([N+:10]([O-:12])=[O:11])=[CH:7][C:2]=1[NH2:1]

参加物

4

反応物 2

HCID 944Nitric AcidHCID 68932,3-Dimethylaniline

生成物 1

HCID 8207862,3-Dimethyl-5-nitroaniline

試薬・触媒・溶媒 1

HCID 1118Sulfuric Acid溶媒2 回

反応条件

温度
12 °C

実験手順

363 g of 2,3-xylidine are run into 1.8 l of pure sulphuric acid while the temperature is kept at 40° C. To this solution, cooled to 12° C., a sulphonitric mixture (132 ml of nitric acid (d=1.52) and 180 ml of pure sulphuric acid) is added dropwise over 1 hour, the temperature not exceeding 15° C. After 15 minutes the mixture is poured onto 6 kg of ice with stirring.

後処理

  1. customis kept at 40° C
  2. customexceeding 15° C

出典と根拠

ORDレコード
ord-c5457cac658944ec86ab2d44d8e9ab0d
出典データセット
uspto-grants-1998_05
特許番号
US05752982

反応ノート

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