Butanal → 1-But-1-enylpyrrolidine

HRID 129100ノート

反応式

HRID 129100 の反応式
[CH:1](=O)[CH2:2][CH2:3][CH3:4].[NH:6]1[CH2:10][CH2:9][CH2:8][CH2:7]1.C(=O)([O-])[O-].[K+].[K+]>C1(C)C=CC=CC=1>[N:6]1([CH:7]=[CH:8][CH2:9][CH3:10])[CH2:4][CH2:3][CH2:2][CH2:1]1

参加物

5

反応物 3

HCID 261ButanalHCID 11430Potassium CarbonateHCID 31268Pyrrolidine

生成物 1

HCID 1396491-But-1-enylpyrrolidine収率 97%

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

108 g of freshly distilled butyraldehyde were added dropwise at 0° C. to a mixture of 213 g of pyrrolidine and 213 g of potassium carbonate. The mixture was allowed to stand overnight at room temperature, diluted with 300 ml of toluene, and the residue was filtered off. The filtrate was then subjected to vacuum distillation at 85° to 90° C. (80 mbar), giving 102 g of 97% pure 1-pyrrolidinobutene, which corresponds to 63.7% of the theoretical yield).

後処理

  1. filtrationthe residue was filtered off
  2. distillationThe filtrate was then subjected to vacuum distillation at 85° to 90° C. (80 mbar)

出典と根拠

ORDレコード
ord-d3697e5b00e64347a24e9c7a729501b3
出典データセット
uspto-grants-1995_11
特許番号
US05466800

反応ノート

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