Ibuprofen, (+-)- → HCID 15948295、化合物

HRID 1294405ノート

反応式

HRID 1294405 の反応式
[OH:1][C:2]([CH:4]([C:6]1[CH:15]=[CH:14][C:9]([CH2:10][CH:11]([CH3:13])[CH3:12])=[CH:8][CH:7]=1)[CH3:5])=[O:3].[OH-].[Na+].O.O.O.O.O.O.[Cl-].[Sr+2:25].[Cl-]>O>[O-:3][C:2]([CH:4]([C:6]1[CH:7]=[CH:8][C:9]([CH2:10][CH:11]([CH3:12])[CH3:13])=[CH:14][CH:15]=1)[CH3:5])=[O:1].[Sr+2:25].[O-:3][C:2]([CH:4]([C:6]1[CH:7]=[CH:8][C:9]([CH2:10][CH:11]([CH3:12])[CH3:13])=[CH:14][CH:15]=1)[CH3:5])=[O:1]

参加物

5

反応物 3

HCID 3672Ibuprofen, (+-)-HCID 14798Sodium HydroxideHCID 6101868Strontium chloride hexahydrate

生成物 1

HCID 15948295HCID 15948295、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

Ibuprofen (2.59 g, 12.5 mmol) was dissolved in water (100 ml) containing sodium hydroxide (0.503 g, 12.5 mmol). A solution of strontium chloride hexahydrate (1.68 g, 6.3 mmol) in water (5 ml) was added. The mixture was stirred for 10 minutes at room temperature and the title compound was isolated by filtration and dried. Yield 1.30 g (44%). Melting point >300° C.

出典と根拠

ORDレコード
ord-17ef2aaa02194c228bbb1d1cb414ffa2
出典データセット
uspto-grants-2007_07
特許番号
US07241460B2

反応ノート

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