(2-Amino-6-fluorophenyl)methanol → 2-Amino-6-fluorobenzaldehyde
反応式
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[CH2:9][OH:10]>C(Cl)(Cl)Cl.[O-2].[Mn+4].[O-2]>[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[CH:9]=[O:10]参加物
4
実験手順
1.44 g (10.2 mmol) (2-amino-6-fluoro-phenyl)-methanol are dissolved in 120 ml chloroform, combined with 4.43 g (51 mmol) manganese(IV)-oxide and stirred for 2 days at ambient temperature. Then excess manganese(IV)-oxide is filtered off through Celite and the solvent is eliminated in vacuo.
後処理
- filtrationThen excess manganese(IV)-oxide is filtered off through Celite
出典と根拠
- ORDレコード
- ord-b108d51035b343a5afea5c1bd1d77e49
- 出典データセット
- uspto-grants-2007_07
- 特許番号
- US07241769B2
反応ノート
読み込み中…