Hydrazine → 2-(Furan-2-yl)aniline

HRID 1294571

反応式

HRID 1294571 の反応式
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[C:10]1[O:11][CH:12]=[CH:13][CH:14]=1)([O-])=O.NN>C(O)C.[Pd]>[O:11]1[CH:12]=[CH:13][CH:14]=[C:10]1[C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[NH2:1]

参加物

5

反応物 2

HCID 9321HydrazineHCID 123772252-(2-Nitrophenyl)furan

生成物 1

HCID 46853502-(Furan-2-yl)aniline

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

113 mg (0.6 mmol) 2-(2-nitro-phenyl)-furan are dissolved in 2 ml of ethanol and combined with 6 mg palladium on activated charcoal (10% Pd). 110 μl of a 35% aqueous hydrazine solution are added to this suspension and the reaction mixture is stirred for 20 h under reflux conditions. The catalyst is suction filtered, the filtrate is combined with 25 ml of water and adjusted to pH 5. This mixture is extracted three times with 10 ml of ethyl acetate. The combined organic phases are dried and the solvent is eliminated in vacuo.

後処理

  1. filtrationfiltered
  2. extractionThis mixture is extracted three times with 10 ml of ethyl acetate
  3. customThe combined organic phases are dried

出典と根拠

ORDレコード
ord-5c9fa89d29a94b56a8b230fd8def624a
出典データセット
uspto-grants-2007_07
特許番号
US07241769B2

関連ノート

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