Hydrazine hydrate (1:1) → HCID 178515921、化合物
反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:17](=O)[C:16]3[C:11](=[CH:12][C:13]([OH:19])=[CH:14][CH:15]=3)[O:10][CH:9]=2)=[CH:4][CH:3]=1.O.[NH2:21][NH2:22]>C(O)C>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:17]([C:16]3[CH:15]=[CH:14][C:13]([OH:19])=[CH:12][C:11]=3[OH:10])=[N:21][NH:22][CH:9]=2)=[CH:4][CH:3]=1参加物
4
実験手順
This compounds was synthesised in the same manner as described in the preceding experiment. 3-(4-Bromo-phenyl)-7-hydroxy-chromen-4-one (0.1 g, 0.3 mmol), hydrazine hydrate (4 ml), ethanol (10 ml). The crude solid product was washed in hot ether to give 4-[4-(4-Bromo-phenyl)-1H-pyrazol-3-yl]-benzene-1,3-diol as a white solid (0.069, 60.6%); Rf 0.44 Cf SM 0.79 ethyl acetate/hexane (75/25).
後処理
- customThis compounds was synthesised in the same manner
- washThe crude solid product was washed in hot ether
出典と根拠
- ORDレコード
- ord-6cea44d539ca4d548c3c6b40f49a33af
- 出典データセット
- uspto-grants-2007_07
- 特許番号
- US07247734B2
反応ノート
読み込み中…