2-Amino-6-nitrobenzothiazole → 2,6-Benzothiazolediamine

HRID 130339

反応式

HRID 130339 の反応式
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([N+:11]([O-])=O)[CH:8]=[CH:7][C:5]=2[N:6]=1.[H][H]>CO.[Pd]>[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([NH2:11])[CH:8]=[CH:7][C:5]=2[N:6]=1

参加物

5

反応物 2

HCID 227042-Amino-6-nitrobenzothiazoleHCID 178418361HCID 178418361、化合物

生成物 1

HCID 215042,6-Benzothiazolediamine収率 99.3%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒2 回

実験手順

2-Amino-6-nitrobenzothiazole (500 mg, 2.56 mmol) was dissolved in methanol (20 mL) and 10% palladium on carbon (50 mg) was added as a slurry in methanol (1 mL). The atmosphere was replaced with hydrogen and the suspension was stirred overnight. The catalyst was removed by suction filtration and the solvent evaporated to afford 2,6-diaminobenzothiazole (420 mg, 99%) as a pale yellow solid.

後処理

  1. customThe catalyst was removed by suction filtration
  2. customthe solvent evaporated

出典と根拠

ORDレコード
ord-2bb820c6c6b84c03b05572fcc80c66e2
出典データセット
uspto-grants-2008_06
特許番号
US07381734B2

関連ノート

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