2-(2,4-Dimethylcyclohex-3-en-1-yl)pyridine → HCID 69218660、化合物

HRID 131088ノート

反応式

HRID 131088 の反応式
[CH3:1][CH:2]1[CH:7]=[C:6]([CH3:8])[CH2:5][CH2:4][CH:3]1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1.C[C@@H]1C[C@H](C)CC[C@@H]1C1C=CC=CN=1>N1C=CC=CC=1>[CH3:1][C@@H:2]1[CH:7]=[C:6]([CH3:8])[CH2:5][CH2:4][C@H:3]1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=1

参加物

4

反応物 2

HCID 179724032-(2,4-Dimethylcyclohex-3-en-1-yl)pyridineHCID 692211552-[(1S,2R,4R)-2,4-Dimethylcyclohexyl]pyridine

生成物 1

HCID 69218660HCID 69218660、化合物

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

The relative amounts of each individual isomer is dependent on the precise conditions used for their formation and whether the hydrogenation reaction is carried out on the mixture of isomers of 2-(2,4-dimethylcyclohex-3-en-1-yl)pyridine or an individual isomer thereof. For example, it has been found that when the hydrogenation reaction is performed on 2-[(1R,2S)-2,4-dimethylcyclohex-3-en-1-yl]pyridine, the major product formed in the resulting mixture of isomers of the pyridine of the invention is 2-[(1S,2R,4R)-2,4-dimethylcyclohexyl]pyridine. By contrast, hydrogenation of 2-[(1R,2R)-2,4-dimethylcyclohex-3-en-1-yl]pyridine conveniently gives a mixture of the 2-[(1R,2R,4R)-2,4-dimethylcyclohexyl]pyridine and 2-[(1R,2R,4S)-2,4-dimethylcyclohexyl]pyridine isomers as the major reaction product.

後処理

  1. customused for their formation and whether the hydrogenation reaction
  2. customthe hydrogenation reaction

出典と根拠

ORDレコード
ord-25d3c85228984d3a81359e7477bed174
出典データセット
uspto-grants-2008_06
特許番号
US07384905B2

反応ノート

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