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Pyridine → 2,2'-Biphenyldimethanol dibenzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Pyridine | HCID 1049 | — |
| 反応物 | Benzoyl chloride | HCID 7412 | — |
| 反応物 | Tetrahydrofuran | HCID 8028 | — |
| 反応物 | (1,1'-Biphenyl)-2,2'-dimethanol | HCID 243265 | — |
| 生成物 | 2,2'-Biphenyldimethanol dibenzoate | HCID 23125865 | 93% |
反応手順
To 0.03 mol 2,2′-biphenyldimethanol was added 30 ml tetrahydrofuran and 0.09 mol pyridine, then added 0.075 mol benzoyl chloride with stirring. The reaction mixture was heated refluxing for 4 hours, cooled and added 20 ml saturated saline. The mixture was extracted with ethyl acetate, and extract was dried over anhydrous sodium sulfate. The solvent was removed. Column chromatography gave 2,2′-biphenyldimethanol dibenzoate as a colorless viscous liquid, and the yield was 93%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07388061B2 |
| 出典データセット | uspto-grants-2008_06 |
| ORD ID | ord-95eff78e70df4997a65f9cd5b2102bbd |
| 出典メモ | uspto-grants-2008_06 |