反应详情

To 0.03 mol 2,2′-biphenyldimethanol was added 30 ml tetrahydrofuran and 0.09 mol pyridine, then added 0.075 mol benzoyl chloride with stirring. The reaction mixture was heated refluxing for 4 hours, cooled and added 20 ml saturated saline. The mixture was extracted with ethyl acetate, and extract was dried over anhydrous sodium sulfate. The solvent was removed. Column chromatography gave 2,2′-biphenyldimethanol dibenzoate as a colorless viscous liquid, and the yield was 93%.

1. temperatureThe reaction mixture was heated
2. temperaturerefluxing for 4 hours
3. temperaturecooled
4. additionadded 20 ml saturated saline
5. extractionThe mixture was extracted with ethyl acetate
6. extractionextract
7. dry with materialwas dried over anhydrous sodium sulfate
8. customThe solvent was removed