(4-Nitrophenyl)methanesulfonamide → 1-(4-Aminophenyl)methanesulfonamide

HRID 132793ノート

反応式

HRID 132793 の反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][S:11]([NH2:14])(=[O:13])=[O:12])=[CH:6][CH:5]=1)([O-])=O>CCO.[Pd]>[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([CH2:10][S:11]([NH2:14])(=[O:12])=[O:13])=[CH:6][CH:5]=1

参加物

4

反応物 1

HCID 2755281(4-Nitrophenyl)methanesulfonamide

生成物 1

HCID 108214071-(4-Aminophenyl)methanesulfonamide

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

step 2—To a solution of (4-nitro-phenyl)-methanesulfonamide (1.18 g, 5.41 mmol) in EtOH (120 mL) was added Pd/C (10%, 118 mg). The mixture was stirred overnight under H2 (balloon pressure), the catalyst was filtered off on a CELITE® pad and the filter cake was washed with EtOH. The filtrate was concentrated in vacuo to afford (4-amino-phenyl)-methanesulfonamide.

後処理

  1. filtrationthe catalyst was filtered off on a CELITE® pad
  2. washthe filter cake was washed with EtOH
  3. concentrationThe filtrate was concentrated in vacuo

出典と根拠

ORDレコード
ord-2f559281ff1b43189d81106cf38fb1ab
出典データセット
uspto-grants-2008_06
特許番号
US07388111B2

反応ノート

読み込み中…